科研项目
1.内蒙古自治区自然科学基金面上项目,外膜囊泡促进布鲁氏菌在巨噬细胞内增殖的作用机制,2025/07-2028/06。
2.呼和浩特市基础研究与应用基础研究项目,外膜囊泡促进布鲁氏菌在巨噬细胞内增殖的作用机制,2025/05-2027/04。
3.内蒙古自然科学基金重大项目,糖富勒烯衍生物的合成及在肿瘤治疗中的作用研究,2020/07-2022/12。
4.国家自然科学基金地区科学基金项目,细胞核FAK对胃癌细胞增殖、迁移及侵袭的调控作用机制,2019/01-2022/12。
5.内蒙古自治区留学回区人员启动项目,FAK在TNFα诱导癌细胞表达炎性细胞因子中的作用机制,2017/10-2020/10。
6.内蒙古自治区自然科学基金博士基金项目, 肿瘤微环境黏着斑激酶在肿瘤坏死因子-α诱导癌细胞炎性因子表达中的调控机制,2016/01-2018/12。
7.内蒙古自治区教育厅重点项目,靶向抑制细胞黏着斑激酶活性治疗胃癌及其腹膜转移癌新方法的研究,2015/01-2017/12。
发表论文
1. Wang N, Yuan N, Lv Z, Fufu Y, Wang Z, Ma M, Zhang Y*, Hao HF*, Rahman FU*. Acetylated monosaccharide functionalized co-ligand based strong anticancer Pt(II) complexes: Synthesis characterization and biological analyses. Journal of Inorganic Biochemistry, 2025, 274:113049.
2. Bai X, Dong C, Shao X, Rahman FU, Hao H, Zhang Y*. Research progress of fullerenes and their derivatives in the field of PDT. European Journal of Medicinal Chemistry, 2024, 271:116398.
3. Liu X, Cao Y, Wang S, Liu J, Hao H*. Extracellular vesicles: powerful candidates in nano-drug delivery systems. Drug Deliv Transl Res, 2024, 14(2):295-311.
4. Lv Z, Liu H, Hao H, Rahman FU, Zhang Y*. Chemical synthesis of oligosaccharides and their application in new drug research. European Journal of Medicinal Chemistry, 2023, 249:115164.
5. Ma Y, Fu Y, Fan X, Ji Q, Duan X, Wang Y, Zhang Y, Wang Z, Hao H*. FAK/IL-8 axis promotes the proliferation and migration of gastric cancer cells. Gastric Cancer, 2023, 26(4):528-541.
6. Shuming Wang, Jiayi Guo, Yang Bai, Cai Sun, Yanhao Wu, Zhe Liu, Xiaofei Liu, Yanfeng Wang, Zhi-gang Wang, Yongming Zhang, Hui-fang Hao*. Bacterial outer membrane vesicles as a candidate tumor vaccine platform. Frontiers in Immunology, 2022.
7. Ji Q, Zhang M, Wang Y, Chen Y, Wang L, Lu X, Bai L, Wang M, Bao L, Hao H*, Wang Z*. Protective effects of chlorogenic acid on inflammatory responses induced by Staphylococcus aureus and milk protein synthesis in bovine mammary epithelial cells. Microbial Pathogenesis, 2022, 171:105726.
8. RuiyuanYao#, YuhaoChen#, HuifangHao#, ZhixinGuo, Xiaoou Cheng, Yuze Ma, Qiang Ji, Xiaoru Yang, Yanfeng Wang, Xihe Li, Zhigang Wang.* Pathogenic effects of inhibition of mTORC1/STAT3 axis facilitates Staphylococcus aureus-induced pyroptosis in human macrophages. Cell communication and signaling.2020,18(1):187.
9. Zhixin Guo#, Xiaoou Chen#, Xue Feng, Keyu Zhao, Meng Zhang, Yuhao Chen, Yanfeng Wang, Hui-fang Hao*, Zhi-gang Wang*. Journal of Agricultural and Food Chemistry, 2019, 67(21):6007-6018.
10. 孙偲,武彦昊,郭佳亿,白杨,郝慧芳 *. 外膜囊泡在肿瘤疫苗中的应用研究进展。生命科学,2022, 11:1431-1441.
11. 王启蒙,樊小莉,郝慧芳 *,王志钢。外泌体在胃癌腹膜转移中的研究进展。生命科学,2022, 8:1001-1009.
12.肖金洋,曹银芳,段晓姣,郝慧芳 *,王志钢。细菌来源的外膜囊泡在病原微生物与宿主细胞相互作用中的研究。中国细胞生物学学报,2022, 5:893-903.
13.黄清宇,杜楚江,张雨竹,曹宏伟,郝慧芳 *. 细胞焦亡研究进展。中国免疫学杂志,2020, 36 (2):245-250.
14.季嫱,马玉泽,郝慧芳 *,王志钢。不同亚细胞定位的黏着斑激酶对肿瘤的调控机制。生命科学,2020, 32 (1):1-8.
15.杨晓茹,陈宇浩,郝慧芳 *. CD36 在炎症反应和脂质代谢中的作用。生命科学,2019, 31 (11):1192-1199.